Li, 311 patient probiotics late treatment study: 12% lower hospital discharge [p=0.68] and 35% slower viral clearance [p=0.001] https://c19p.org/li10
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The role of probiotics in coronavirus disease-19 infection in Wuhan: A retrospective study of 311 severe patients
et al., International Immunopharmacology, doi:10.1016/j.intimp.2021.107531
Retrospective 311 severe condition hospitalized patients in China, 123 treated with probiotics, showing slower viral clearance and recovery with treatment. Authors note that probiotics were able to moderate immunity and decrease the incidence of secondary infections.The immune effects of probiotics are strain-specific.
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risk of no hospital discharge, 11.8% higher, RR 1.12, p = 0.68, treatment 30 of 123 (24.4%), control 41 of 188 (21.8%).
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time to discharge, 60.0% higher, relative time 1.60, p < 0.001, treatment 123, control 188.
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time to viral-, 35.3% higher, relative time 1.35, p < 0.001, treatment 123, control 188.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Li et al., 3/5/2021, retrospective, China, Asia, peer-reviewed, 7 authors, average treatment delay 13.0 days.
Late treatment
is less effective
is less effective
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