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0 0.5 1 1.5 2+ Recovery 54% Improvement Relative Risk Recovery, exc. ICU 54% c19probiotics.com Santinelli et al. Probiotics for COVID-19 LONG COVID Favors probiotics Favors control
Santinelli, 58 patient probiotics long COVID study: 54% improved recovery [p<0.0001] https://c19p.org/santinelli
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Oral Bacteriotherapy Reduces the Occurrence of Chronic Fatigue in COVID-19 Patients
Santinelli et al., Frontiers in Nutrition, doi:10.3389/fnut.2021.756177
12 Jan 2022    Source   PDF   Share   Tweet
Retrospective 58 hospitalized patients, 24 receiving probiotics during hospitalization, showing significantly lower fatigue six months post discharge with treatment.
The immune effects of probiotics are strain-specific.
risk of no recovery, 54.3% lower, RR 0.46, p < 0.001, treatment 10 of 24 (41.7%), control 31 of 34 (91.2%), NNT 2.0, 6 months post discharge.
risk of no recovery, 54.0% lower, RR 0.46, p < 0.001, treatment 9 of 22 (40.9%), control 24 of 27 (88.9%), NNT 2.1, 6 months post discharge, excluding ICU patients.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Santinelli et al., 12 Jan 2022, retrospective, Italy, peer-reviewed, survey, 14 authors.
Contact: giancarlo.ceccarelli@uniroma1.it.
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